Friend or foe

نویسندگان

  • Johann Röhrl
  • Edward K. Geissler
  • Thomas Hehlgans
چکیده

For many years, β-defensins were best known for their antimicrobial activity. However, β-defensins also exert immunomodulatory functions, such as the chemotactic recruitment of immune cells via chemokine receptors. We demonstrated that mouse β-defensin 14 recruits CCR6(+) B cells into fibrosarcomas, resulting in enhanced angiogenesis and tumor development.

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منابع مشابه

Apocrine Metaplasia in Intraductal Papilloma with Foci of DCIS: A Friend or Foe?

Malignant papillary neoplasms of the breast comprise a number of microscopically distinct lesions, where apocrine metaplasia is commonly found in papillomas compared to other papillary lesions including papillary carcinomas. However, association of apocrine metaplasia in papilloma with Ductal Carcinoma in Situ (DCIS) is not very well defined. The lesions with apocrine metaplasia are not only di...

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عنوان ژورنال:

دوره 1  شماره 

صفحات  -

تاریخ انتشار 2012